Lipitor

Pronunciation: a-TOR-va-STAT-in
Generic Name: Atorvastatin
Brand Name: Lipitor

Lipitor is used for:

Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to reduce the risk of heart attack, stroke, chest pain caused by angina, or blood vessel blockage. It is also used in certain patients to reduce the risk of hospitalization for congestive heart failure, or the need for medical procedures to open blocked heart blood vessels. It may also be used for other conditions as determined by your doctor.

Lipitor is an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.

Do NOT use Lipitor if:

• you are allergic to any ingredient in Lipitor


• you have liver problems or unexplained abnormal liver function tests


• you are pregnant or breast-feeding


• you are taking conivaptan, mibefradil, or telaprevir

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lipitor:

Some medical conditions may interact with Lipitor. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are able to become pregnant


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have low blood pressure, kidney problems, diabetes, thyroid problems, muscle problems, or a serious infection


• if you have metabolism, hormonal, or electrolyte problems


• if you drink alcohol or have a history of seizures, liver problems, or alcohol abuse


• if you are scheduled for major surgery, or have recently had major surgery, a serious injury, or a stroke

Some MEDICINES MAY INTERACT with Lipitor. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, azole antifungals (eg, fluconazole, itraconazole), colchicine, conivaptan, cyclosporine, daptomycin, delavirdine, diltiazem, dronedarone, fibrates (eg, clofibrate, gemfibrozil), fusidic acid, HCV protease inhibitors (eg, boceprevir, telaprevir), HIV protease inhibitors (eg, ritonavir), imatinib, macrolides (eg, clarithromycin, erythromycin), mibefradil, nefazodone, niacin, quinine, streptogramins (eg, dalfopristin), telithromycin, verapamil, or voriconazole because they may increase the risk of muscle or kidney problems


• Bosentan, carbamazepine, efavirenz, rifamycins (eg, rifampin), or St. John's wort because they may decrease Lipitor's effectiveness


• Cimetidine, digoxin, certain hormonal contraceptives (eg, certain birth control pills), ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Lipitor

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lipitor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lipitor:

Use Lipitor as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lipitor by mouth with or without food.


• Swallow Lipitor whole. Do not break, crush, or chew before swallowing.


• Eating grapefruit or drinking grapefruit juice may increase the amount of Lipitor in your blood, which may increase your risk for serious side effects. The risk may be greater with large amounts of grapefruit or grapefruit juice. Avoid large amounts of grapefruit or grapefruit juice (eg, more than one quart daily). Talk with your doctor or pharmacist if you have questions about including grapefruit or grapefruit juice in your diet while you are taking Lipitor.


• Continue to take Lipitor even if you feel well. Do not miss any doses.


• If you miss a dose of Lipitor, take it as soon as possible if you remember within 12 hours of the missed dose. If it is more than 12 hours since the missed dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lipitor.

Important safety information:

• Drinking alcohol daily or in large amounts may increase the risk of liver problems with Lipitor. Check with your doctor before drinking alcohol while you are taking Lipitor.


• Follow the diet and exercise program given to you by your health care provider.


• Tell your doctor or dentist that you take Lipitor before you receive any medical or dental care, emergency care, or surgery.


• Women who may become pregnant should use effective birth control while taking Lipitor. Check with your doctor if you have questions about using birth control.


• Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort.


• Lab tests, including blood cholesterol levels, creatine phosphokinase (CPK) levels, and liver function, may be performed while you use Lipitor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Lipitor with caution in the ELDERLY; they may be more sensitive to its effects, especially muscle problems.


• Lipitor should be used with extreme caution in CHILDREN younger than 10 years old and in those who have not reached puberty; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Lipitor if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Lipitor is found in breast milk. Do not breast-feed while taking Lipitor.

Possible side effects of Lipitor:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; joint pain; mild sore throat; nausea; runny or stuffy nose; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); change in the amount of urine produced; dark urine; muscle pain, tenderness, or weakness (with or without fever or fatigue); painful, difficult, or frequent urination; pale stools; persistent loss of appetite; persistent pain, soreness, redness, or swelling of a tendon or joint; red, swollen, blistered, or peeling skin; severe or persistent nausea, vomiting, or stomach pain; unusual tiredness; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lipitor side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lipitor:

Store Lipitor at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lipitor out of the reach of children and away from pets.

General information:

• If you have any questions about Lipitor, please talk with your doctor, pharmacist, or other health care provider.


• Lipitor is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lipitor. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lipitor resources

• Lipitor Side Effects (in more detail)
• Lipitor Use in Pregnancy & Breastfeeding
• Drug Images
• Lipitor Drug Interactions
• Lipitor Support Group
• 26 Reviews for Lipitor - Add your own review/rating

• Lipitor Prescribing Information (FDA)


• Lipitor Consumer Overview


• Lipitor Monograph (AHFS DI)


• Lipitor Advanced Consumer (Micromedex) - Includes Dosage Information


• Atorvastatin Prescribing Information (FDA)

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